Sonia Arrison

Living longer isn’t the real breakthrough.
Living well for longer is.

For most of history, a longer life meant more years of sickness or weakness. Medicine focused on keeping people alive - not on keeping them healthy, capable, and independent.

That’s the problem Sonia Arrison set out to challenge early on.

More than a decade ago, her book 100 Plus predicted a future where healthspan - not just lifespan - would define progress, arguing that biology, technology, and society would need to evolve together.

Today, Sonia helps turn that vision into action.

She is a longevity investor and advisor at Felicis, runs her own angel fund 100 Plus Capital, and is a venture partner at Portfolia, where she invests across AI-powered diagnostics, regenerative medicine, women’s health, and preventative care.

She also chairs The Alliance for Longevity Initiatives Initiatives, working to bring longevity science into public policy.

Her belief is simple: there is no miracle cure. The real shift comes from personalized biology, powered by AI, that helps people stay healthier as they age.

I’ve followed Sonia’s work for years. She is consistently one of the most thoughtful investors and clear-headed thinkers in longevity.

Last updated: January 2026